The Tower's Prelude places you in the moth-eaten shoes of Constance Nightingale, a 16th-century Shakespearean woman. A tired, depressed, and forlorn woman plagued by a 'curse' all her life, fate finally sees Constance hanged. Becoming something akin to a spirit, she is swept away to a world like and unlike our own when a magical apocalypse is in its earliest infancy. Lost in a densely populated jungle of concrete, she resorts to what life taught her—hide, run, steal, adapt. Yet Constance quickly realizes that everything she touches is either made sick by her ghostly body or devoured by the noose that haunts her long after her death.